Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Palmar-plantar erythrodysaesthesia syndrome
ADR ID BADD_A03260
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.07      Sensory abnormalities NEC
17.02.07.009      Palmar-plantar erythrodysaesthesia syndrome
23      Skin and subcutaneous tissue disorders
23.07      Skin and subcutaneous tissue disorders NEC
23.07.04      Skin and subcutaneous conditions NEC
23.07.04.001      Palmar-plantar erythrodysaesthesia syndrome
Description Not Available
MedDRA Code 10033553
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hand and foot syndrome | Hand-and-foot syndrome | Palmar-plantar erythrodysaesth. | Palmar-plantar erythrodysaesthesia syndrome | Hand and foot syndrome secondary to chemotherapy | Palmar-plantar erythrodysesthesia syndrome | Palmar-plantar erythema | Hand and foot skin reaction | Acral erythema | Genital erythrodysesthesia | Genital erythrodysaesthesia | Toxic erythema of chemotherapy
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Broad substrate specificity ATP-binding cassette transporter ABCG2Q9UNQ0T56556
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01687Pazopanib0.014919%
BADD_D01688Pazopanib hydrochloride--
BADD_D01804Posaconazole0.021671%
BADD_D01834Prednisone--
BADD_D01835Pregabalin--
BADD_D01911Ramucirumab--
BADD_D01922Regorafenib0.136935%
BADD_D02058Sorafenib0.125213%
BADD_D02100Sunitinib0.111626%
BADD_D02101Sunitinib malate--
BADD_D02160Terbinafine0.001058%
BADD_D02253Trabectedin0.001332%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02334Vandetanib0.000799%
BADD_D02344Vemurafenib0.004764%
BADD_D02392Zoledronic acid--
BADD_D02483Ribociclib0.000799%
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